Research at the Center for Biofilm Engineering is driven by industrial, environmental, and health issues of national importance. CBE research has contributed new insights into microbial processes in a wide variety of contexts.
- is motivated by industrial concerns and involvement of industry partners;
- is conducted at multiple scales of observation, from molecular to field-scale;
- involves interdisciplinary investigations;
- provides relevant research opportunities for undergraduate and graduate students;
- is enhanced by productive collaborations with researchers at other institutions;
- is funded by competitive grants and industrial memberships; and
- produces both fundamental and applied results.
The CBE's long history of research success results from adaptability to new information and analytical technologies and flexibility in addressing biofilm issues in comprehensive ways, using its deep bench of MSU researchers with diverse specialties in biofilm studies. Discover the breadth and depth of the CBE's research team by exploring our Affiliated Faculty.
APPLIED RESEARCH AREAS & PROJECTS
- Biofilm control strategies: antimicrobial efficacy | biocides | bioelectric effect | disinfectants | inhibitory coatings | bioactive compound
- Energy solutions: biofuels | product souring | coalbed methane production | microbial fuel cells
- Environmental technologies: bioremediation | wetlands | CO2 sequestration | biobarriers | biomineralization | microbes & mining issue
- Health/medical biofilms: chronic wound healing | catheter infections | oral health | food safety
- Industrial systems & processes: biofouling | biocorrosion | product contamination | microbe-metal interaction
- Standardized methods: product claims | regulatory issues | ASTM methods acceptance
- Water systems: drinking water quality | premise plumbing | water treatment | distribution systems
- Biofilms in nature: microbes in hot & cold environments | role of biofilms in natural processes | biomimetics | biogeochemistry
- Cellular/intracellular: phenotype | genetics | metabolic pathways | proteomics
- Multicellular/extracellular: flow and transport in biofilm systems | material properties | quorum sensing | structure-function | heterogeneities | matrix
- Ecology/physiology: population characterization | spatial and temporal population dynamics | anaerobic systems
ANALYTICAL TOOLS & TECHNIQUES
- Instrumentation: microscopy | nuclear magnetic resonance imaging | gas chromatography | microfluidics | biosensors | 3-D hydrogel printing
- Methods development: experimental design | variability | ruggedness | repeatability | statistical evaluation
- Modeling: cellular automata modeling | mathematics | hydrodynamics
- Basic microbiology techniques: total and direct counts | MIC determination | viable cell counts
- Molecular biology techniques: DNA extraction | PCR | DGGE | microarrays | sequencing
Slideshow: Why companies need the CBE
“CBE documentary on real-world problems of biofilms”
“Think Outside Expectations: MSU's Women in Engineering”
“Impacting healthcare sciences nationally and internationally through research, education,
**CBE featured at minute 2:25. Video courtesy of MSU's Division of Health Sciences.
“Discover the Center for Biofilm Engineering at MSU”